Dr. med. Tamara Rügamer untersucht in einem Drittmittel-geförderten Projekt (ReForM A, Universitätsklinikum Regensburg, 1.11.2018-30.10.2019) mit Prof. Jutta Eichler, Pharmazeutische Chemie, FAU Erlangen-Nürnberg, den inhibitorischen Effekt von Peptiden aus dem Hüllprotein von Hepatitis G-Virus (HGV) auf den Eintritt von HIV-1 in die Zielzelle.
Publikationen:
- Huhmann S, Nyakatura EK, Rohrhofer A, Moschner J, Schmidt B, Eichler J, Roth C, Koksch B. Systematic Evaluation of Fluorination as Modification for Peptide-Based Fusion Inhibitors against HIV-1 Infection. Chembiochem. 2021 Dec 10;22(24):3443-3451. doi: 10.1002/cbic.202100417.
- Exploring Viral Interference Using Peptides: Molecular Determinants of HIV-1 Inhibition by a Peptide Derived from Human Pegivirus-1 Envelope Protein E2. ChemMedChem. 2021 Apr 20;16(8):1290-1296.
- Ruegamer T, Hoffmann R, Rohrhofer A, Audebert F, Salzberger B, Korn K, Schuster P, Eichler J, Schmidt B. Inhibition of HIV-1 infection by human pegivirus type 1-derived peptides is affected by human pegivirus type 1 genotype and HIV-1 coreceptor tropism. AIDS. 2018 Sep 10;32(14):1951-1957.
- Haußner C, Damm D, Nirschl S, Rohrhofer A, Schmidt B, Eichler J. Peptide Paratope Mimics of the Broadly Neutralizing HIV-1 Antibody b12. Chembiochem. 2017 Apr 4;18(7):647-653.
- Groß A, Brox R, Damm D, Tschammer N, Schmidt B, Eichler J. Ligand selectivity of a synthetic CXCR4 mimetic peptide. Bioorg Med Chem. 2015 Jul 15;23(14):4050-5.
- Groß A, Rödel K, Kneidl B, Donhauser N, Mössl M, Lump E, Münch J, Schmidt B, Eichler J. Enhancement and induction of HIV-1 infection through an assembled peptide derived from the CD4 binding site of gp120. Chembiochem. 2015 Feb 9;16(3):446-54.
- Groß A, Möbius K, Haußner C, Donhauser N, Schmidt B, Eichler J. Mimicking Protein-Protein Interactions through Peptide-Peptide Interactions: HIV-1 gp120 and CXCR4. Front Immunol. 2013 Sep 3;4:257.