Arbeitsgruppe Prof. Dr. Dr. André Gessner
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andre.gessner@ukr.de | |||||
Termine des Journal Club, Donnerstag 8:30 Uhr, bitte hier klicken Termine des Arbeitsgruppenseminars, Mittwoch 8:30 Uhr, bitte hier klicken |
UNSERE PROJEKTE
Alle aktuellen Projekte unserer Arbeitsgruppe auf einen Blick:
Investigating the Role of Paget’s Disease of Bone Risk Factor p62/Sqstm1 in Osteoclast Differentiation and activity
Paget’s disease of bone (PDB) depicts a severe condition of pathological bone abnormalities affecting about 2-5% of the Caucasian population … Weiterlesen Investigating the Role of Paget’s Disease of Bone Risk Factor p62/Sqstm1 in Osteoclast Differentiation and activity
Regulation der T-Zell-Antworten im Leishmaniose-Mausmodell
Leishmaniose wird durch intrazelluläre, einzellige Parasiten der Gattung Leishmania ausgelöst und betrifft jährlich weltweit mehr als 12 Millionen Menschen. Mehr … Weiterlesen Regulation der T-Zell-Antworten im Leishmaniose-Mausmodell
Characterization of bactericidal/permeability increasing protein expression and function based on newly developed transgenic mouse models
Bactericidal/permeability increasing protein (BPI) belongs to the highly conserved family of lipid-transfer-proteins. BPI is synthesized early during myelopoiesis by granulocyte … Weiterlesen Characterization of bactericidal/permeability increasing protein expression and function based on newly developed transgenic mouse models
SFB 1371 „Microbiome Signatures – Funktionelle Relevanz des Mikrobioms im Verdauungstrakt“
Der SFB „Microbiome Signatures – Funktionelle Relevanz des Mikrobioms im Verdauungstrakt“ untersucht die Wechselwirkungen, die zwischen der Zusammensetzung des Mikrobioms … Weiterlesen SFB 1371 „Microbiome Signatures – Funktionelle Relevanz des Mikrobioms im Verdauungstrakt“
MITARBEITER
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UNSERE NEWS
Alle aktuellen News unserer Arbeitsgruppe auf einen Blick:
Wissenschaftliche Originalarbeiten der letzten Jahre
Schuderer JG, Hoferer F, Eichberger J, Fiedler M, Gessner A, Hitzenbichler F, Gottsauner M, Maurer M, Meier JK, Reichert TE, Ettl T.
Predictors for prolonged and escalated perioperative antibiotic therapy after microvascular head and neck reconstruction: a comprehensive analysis of 446 cases.
Head Face Med. 2024 Oct 15;20(1):58. doi: 10.1186/s13005-024-00463-9.PMID: 39402552
Röhrl A, Klawonn F, Füchtmeier B, Wulbrand C, Gessner A, Zustin J, Ambrosch A.
Correction: Results of a monocentric field study: value of histology compared to sonication method and conventional tissue culture in the diagnosis of periprosthetic joint infection (PJI).
Infection. 2024 Oct 21. doi: 10.1007/s15010-024-02399-3. Online ahead of print.PMID: 39432020 No abstract available.
Turner AM, Li L, Monk IR, Lee JYH, Ingle DJ, Portelli S, Sherry NL, Isles N, Seemann T, Sharkey LK, Walsh CJ, Reid GE, Nie S, Eijkelkamp BA, Holmes NE, Collis B, Vogrin S, Hiergeist A, Weber D, Gessner A, Holler E, Ascher DB, Duchene S, Scott NE, Stinear TP, Kwong JC, Gorrie CL, Howden BP, Carter GP.
Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin.
Nature. 2024 Oct 23. doi: 10.1038/s41586-024-08095-4. Online ahead of print.PMID: 39443798
Winter L, Mendelsohn DH, Walter N, Popp D, Geis S, Niedermair T, Mamilos A, Gessner A, Salzberger B, Pfister K, Stroszczynski C, Alt V, Rupp M, Brochhausen C.
Multidisciplinary Teams in Musculoskeletal Infection - From a Pathologist's Perspective.
Pathol Res Pract. 2024 Aug 12;262:155539. doi: 10.1016/j.prp.2024.155539. Online ahead of print.PMID: 39151251
Alt V, Gessner A, Merabishvili M, Hitzenbichler F, Mannala GK, Peterhoff D, Walter N, Pirnay JP, Hiergeist A, Rupp M.
Case report: Local bacteriophage therapy for fracture-related infection with polymicrobial multi-resistant bacteria: hydrogel application and postoperative phage analysis through metagenomic sequencing.
Front Med (Lausanne). 2024 Jul 12;11:1428432. doi: 10.3389/fmed.2024.1428432. eCollection 2024.PMID: 39071087 Free PMC article.
Weber D, Meedt E, Poeck H, Thiele-Orberg E, Hiergeist A, Gessner A, Holler E
Fecal Microbiota Transfer in Acute Graft-versus-Host Disease following Allogeneic Stem Cell Transplantation. .
Visc Med. 2024 Mar 26:1-6. doi: 10.1159/000538303. PMID: 39047173
Schreiber L, Ghimire S, Hiergeist A, Renner K, Althammer M, Babl N, Peuker A, Schoenhammer G, Hippe K, Gessner A, Albrecht C, Pielmeier F, Büttner-Herold M, Bruns H, Hoffmann P, Herr W, Holler E, Peter K, Kreutz M, Matos C.
Strain specific differences in vitamin D3 response: impact on gut homeostasis.
Front Immunol. 2024 Mar 1;15:1347835. doi: 10.3389/fimmu.2024.1347835. eCollection 2024.PMID: 38495883 Free PMC article.
Schulz-Kuhnt A, Rühle K, Javidmehr A, Döbrönti M, Biwank J, Knittel S, Neidlinger P, Leupold J, Liu LJ, Dedden M, Taudte RV, Gessner A, Fromm MF, Mielenz D, Kreiss L, Waldner MJ, Schürmann S, Friedrich O, Dietel B, López-Posadas R, Plattner C; TRR241 IBDome Consortium; Zundler S, Becker C, Atreya R, Neurath MF, Atreya I.
ATP citrate lyase (ACLY)-dependent immunometabolism in mucosal T cells drives experimental colitis in vivo.
Gut. 2024 Mar 7;73(4):601-612. doi: 10.1136/gutjnl-2023-330543.PMID: 38176897
Bauswein M, Knoll G, Schmidt B, Gessner A, Hemmer B, Flaskamp M.
No evidence of an association of multiple sclerosis (MS) with Borna disease virus 1 (BoDV-1) infections in patients within an endemic region: a retrospective pilot study.
Infection. 2024 Feb;52(1):243-247. doi: 10.1007/s15010-023-02099-4. Epub 2023 Oct 9.PMID: 37814203
Thiele Orberg E, Meedt E, Hiergeist A, Xue J, Heinrich P, Ru J, Ghimire S, Miltiadous O, Lindner S, Tiefgraber M, Göldel S, Eismann T, Schwarz A, Göttert S, Jarosch S, Steiger K, Schulz C, Gigl M, Fischer JC, Janssen KP, Quante M, Heidegger S, Herhaus P, Verbeek M, Ruland J, van den Brink MRM, Weber D, Edinger M, Wolff D, Busch DH, Kleigrewe K, Herr W, Bassermann F, Gessner A, Deng L, Holler E, Poeck H.
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation.
Nat Cancer. 2024 Jan;5(1):187-208. doi: 10.1038/s43018-023-00669-x. Epub 2024 Jan 3.PMID: 38172339
Manook A, Baghai TC, Riebel M, Nothdurfter C, Schwarzbach JV, Gessner A, Rupprecht R, Hiergeist A.
Short-term effects of etifoxine on human gut microbiome in healthy men.
Front Neurosci. 2023 Nov 14;17:1188847. doi: 10.3389/fnins.2023.1188847. eCollection 2023.PMID: 38075272 Free PMC article.
Bauswein M, Knoll G, Schmidt B, Gessner A, Hemmer B, Flaskamp M.
No evidence of an association of multiple sclerosis (MS) with Borna disease virus 1 (BoDV-1) infections in patients within an endemic region: a retrospective pilot study.
Infection. 2023 Oct 9. doi: 10.1007/s15010-023-02099-4 Online ahead of print. PMID: 37814203
Gessner A, Klimek L, Kuchar E, Stelzmueller I, Fal AM, Kardos P.
Potential Saving of Antibiotics for Respiratory Infections in Several European Countries: Insights from Market Research Data.
Antibiotics (Basel). 2023 Jul 11;12(7):1174. doi: 10.3390/antibiotics12071174.PMID: 37508270
Jarosch S, Köhlen J, Ghimire S, Orberg ET, Hammel M, Gaag D, Evert M, Janssen KP, Hiergeist A, Gessner A, Weber D, Meedt E, Poeck H, D'Ippolito E, Holler E, Busch DH.
Multimodal immune cell phenotyping in GI biopsies reveals microbiome-related T cell modulations in human GvHD.
Cell Rep Med. 2023 Jul 18;4(7):101125. doi: 10.1016/j.xcrm.2023.101125.PMID: 37467715
Holzinger JM, Toelge M, Werner M, Ederer KU, Siegmund HI, Peterhoff D, Blaas SH, Gisch N, Brochhausen C, Gessner A, Bülow S.
Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from people with cystic fibrosis.
Elife. 2023 Jul 18;12:e86369. doi: 10.7554/eLife.86369.PMID: 37461324 Free PMC article.
Weber D, Hiergeist A, Weber M, Ghimire S, Salzberger B, Wolff D, Poeck H, Gessner A, Edinger M, Herr W, Meedt E, Holler E.
Restrictive versus permissive use of broad-spectrum antibiotics in patients receiving allogeneic SCT and early fever due to cytokine release syndrome: Evidence for beneficial microbiota protection without increase of infectious complications.
Clin Infect Dis. 2023 Jun 30:ciad389. doi: 10.1093/cid/ciad389. Online ahead of print.PMID: 37386935
Hijazi MA, Gessner A, El-Najjar N.
Repurposing of Chronically Used Drugs in Cancer Therapy: A Chance to Grasp.
Cancers (Basel). 2023 Jun 15;15(12):3199. doi: 10.3390/cancers15123199. PMID: 37370809 Free PMC article. Review.
Scheidler L, Hippe K, Ghimire S, Weber D, Weber M, Meedt E, Hoffmann P, Lehn P, Burkhardt R, Mamilos A, Edinger M, Wolff D, Poeck H, Evert M, Gessner A, Herr W, Holler E.
Intestinal IgA positive plasma cells are highly sensitive indicators of alloreaction early after allogeneic transplantation and associate with both, graft-versus-host disease and relapse related mortality.
Haematologica. 2023 Jun 1. doi: 10.3324/haematol.2022.282188. Online ahead of print.PMID: 37259539
Herold JM, Nano J, Gorski M, Winkler TW, Stanzick KJ, Zimmermann ME, Brandl C, Peters A, Koenig W, Burkhardt R, Gessner A, Heid IM, Gieger C, Stark KJ.
Polygenic scores for estimated glomerular filtration rate in a population of general adults and elderly - comparative results from the KORA and AugUR study.
BMC Genom Data. 2023 May 25;24(1):28. doi: 10.1186/s12863-023-01130-9.PMID: 37231333 Free PMC article.
Hoelz H, Heetmeyer J, Tsakmaklis A, Hiergeist A, Siebert K, De Zen F, Häcker D, Metwaly A, Neuhaus K, Gessner A, Vehreschild MJGT, Haller D, Schwerd T.
Is Autologous Fecal Microbiota Transfer after Exclusive Enteral Nutrition in Pediatric Crohn's Disease Patients Rational and Feasible? Data from a Feasibility Test.
Nutrients. 2023 Apr 2;15(7):1742. doi: 10.3390/nu15071742.PMID: 37049583
Weber D, Weber M, Meedt E, Ghimire S, Wolff D, Edinger M, Poeck H, Hiergeist A, Gessner A, Ayuk F, Roesler W, Wölfl M, Kraus S, Zeiser R, Bertrand H, Bader P, Ullrich E, Eder M, Gleich S, Young R, Herr W, Levine JE, Ferrara JLM, Holler E.
Reg3α concentrations at day of allogeneic stem cell transplantation predict outcome and correlate with early antibiotic use.
Blood Adv. 2023 Apr 11;7(7):1326-1335. doi: 10.1182/bloodadvances.2022008480.PMID: 36350750
Donhauser FJ, Zimmermann ME, Steinkirchner AB, Wiegrebe S, Dietl A, Brandl C, Burkhardt R, Gessner A, Schweda F, Bergler T, Schäffner E, Böger CA, Kronenberg F, Luchner A, Stark KJ, Heid IM.
Cardiovascular Risk Factor Control in 70- to 95-Year-Old Individuals: Cross-Sectional Results from the Population-Based AugUR Study.
J Clin Med. 2023 Mar 7;12(6):2102. doi: 10.3390/jcm12062102.PMID: 36983106
Hiergeist A, Ruelle J, Emler S, Gessner A.
Reliability of species detection in 16S microbiome analysis: Comparison of five widely used pipelines and recommendations for a more standardized approach.
PLoS One. 2023 Feb 16;18(2):e0280870. doi: 10.1371/journal.pone.0280870. PMID: 36795699; PMCID:PMC9934417.
Bauswein M, Eidenschink L, Knoll G, Neumann B, Angstwurm K, Zoubaa S, Riemenschneider MJ, Lampl BMJ, Pregler M, Niller HH, Jantsch J, Gessner A, Eberhardt Y, Huppertz G, Schramm T, Kühn S, Koller M, Drasch T, Ehrl Y, Banas B, Offner R, Schmidt B, Banas MC.
Human Infections with Borna Disease Virus 1 (BoDV-1) Primarily Lead to Severe Encephalitis: Further Evidence from the Seroepidemiological BoSOT Study in an Endemic Region in Southern Germany.
Viruses. 2023 Jan 9;15(1):188. doi: 10.3390/v15010188. PMID: 36680228; PMCID:PMC9867173.
Eidenschink L, Knoll G, Tappe D, Offner R, Drasch T, Ehrl Y, Banas B, Banas MC, Niller HH, Gessner A, Köstler J, Lampl BMJ, Pregler M, Völkl M, Kunkel J, Neumann B, Angstwurm K, Schmidt B, Bauswein M.
IFN-γ-Based ELISpot as a New Tool to Detect Human Infections with Borna Disease Virus 1 (BoDV-1): A Pilot Study.
Viruses. 2023 Jan 10;15(1):194. doi: 10.3390/v15010194. PMID: 36680234; PMCID:PMC9864614.
Nausch B, Bittner CB, Höller M, Abramov-Sommariva D, Hiergeist A, Gessner A.
Contribution of Symptomatic, Herbal Treatment Options to Antibiotic Stewardship and Microbiotic Health.
Antibiotics (Basel). 2022 Sep 29;11(10):1331. doi:10.3390/antibiotics11101331. PMID: 36289988; PMCID: PMC9598931.
Pfab C, Abgaryan A, Danzer B, Mourtada F, Ali W, Gessner A, El-Najjar N.
Ceftazidime and cefepime antagonize 5-fluorouracil's effect in colon cancercells.
BMC Cancer. 2022 Jan 31;22(1):125. doi: 10.1186/s12885-021-09125-4. PMID:35100987; PMCID: PMC8802503.
Meedt E, Hiergeist A, Gessner A, Dettmer K, Liebisch G, Ghimire S, Poeck H, Edinger M, Wolff D, Herr W, Holler E, Weber D.
Prolonged Suppression of Butyrate-Producing Bacteria Is Associated With Acute Gastrointestinal Graft-vs-Host Disease and Transplantation-Related Mortality After Allogeneic Stem Cell Transplantation.
Clin Infect Dis. 2022 Mar 1;74(4):614-621. doi:10.1093/cid/ciab500. PMID: 34043764.
Matos C, Mamilos A, Shah PN, Meedt E, Weber D, Ghimire S, Hiergeist A, Gessner A, Dickinson A, Dressel R, Walter L, Stark K, Heid IM, Poeck H, Edinger M, Wolff D, Herr W, Holler E, Kreutz M, Ghimire S.
Downregulation of the vitamin D receptor expression during acute gastrointestinal graft versus host disease is associated with poor outcome after allogeneic stem cell transplantation.
Front Immunol. 2022 Oct 20;13:1028850. doi: 10.3389/fimmu.2022.1028850. PMID:36341397; PMCID: PMC9632171.
Simon M, Gerlach RG, Pfeifer Y, Pfennigwerth N, Gatermann SG, Schröder A, Hiergeist A, Hamprecht A, Rügamer T, Gessner A, Jantsch J. Increased zinc levels facilitate phenotypic detection of ceftazidime-avibactam resistance in metallo-β-lactamase-producing Gram-negative bacteria.
Front Microbiol. 2022 Nov 22;13:977330. doi: 10.3389/fmicb.2022.977330. PMID: 36483203; PMCID: PMC9723239.
Weber DA, Weber M, Meedt E, Ghimire S, Wolff D, Edinger M, Poeck H, Hiergeist A, Gessner A, Ayuk FA, Roesler W, Wolfl M, Kraus S, Zeiser R, Bertrand H, Bader P, Ullrich E, Eder M, Gleich S, Young R, Herr W, Levine JE, Ferrara JL, Holler E.
Reg3α levels at day of allogeneic stem cell transplantation predict outcome and correlate with early antibiotic use.
Blood Adv. 2022 Nov 9:bloodadvances.2022008480. doi: 10.1182/bloodadvances.2022008480. Epub ahead of print. PMID: 36350750.
Magnus CL, Hiergeist A, Schuster P, Rohrhofer A, Medenbach J, Gessner A, Peterhoff D, Schmidt B.
Targeted escape of SARS-CoV-2 in vitro from monoclonal antibody S309, the precursor of sotrovimab. Front. Immunol. 2022 Aug 24 doi:10.3389/fimmu.2022.966236
Mao X, Hiergeist A, Auer DL, Scholz KJ, Muehler D, Hiller KA, Maisch T, Buchalla W, Hellwig E, Gessner A, Al-Ahmad A, Cieplik F.
Ecological Effects of Daily Antiseptic Treatment on Microbial Composition of Saliva-Grown Microcosm Biofilms and Selection of Resistant Phenotypes.
Front Microbiol. 2022 Jun 30;13:934525. doi: 10.3389/fmicb.2022.934525. eCollection 2022.PMID: 35847089 Free PMC article.
Einhauser S, Peterhoff D, Beileke S, Günther F, Niller HH, Steininger P, Knöll A, Korn K, Berr M, Schütz A, Wiegrebe S, Stark KJ, Gessner A, Burkhardt R, Kabesch M, Schedl H, Küchenhoff H, Pfahlberg AB, Heid IM, Gefeller O, Überla K, Wagner R. Time Trend in SARS-CoV-2 Seropositivity, Surveillance Detection- and Infection Fatality Ratio until Spring 2021 in the Tirschenreuth County-Results from a Population-Based Longitudinal Study in Germany. Viruses. 2022 May 27;14(6):1168. doi: 10.3390/v14061168
Stumptner C, Stadlbauer V, O'Neil D, Gessner A, Hiergeist A, Zatloukal K, Abuja PM.The Pre-Analytical CEN/TS Standard for Microbiome Diagnostics-How Can Research and Development Benefit? Nutrients. 2022 May 9;14(9):1976. doi: 10.3390/nu14091976.PMID: 35565946 Free PMC article.
de Castilhos J, Zamir E, Hippchen T, Rohrbach R, Schmidt S, Hengler S, Schumacher H, Neubauer M, Kunz S, Müller-Esch T, Hiergeist A, Gessner A, Khalid D, Gaiser R, Cullin N, Papagiannarou SM, Beuthien-Baumann B, Krämer A, Bartenschlager R, Jäger D, Müller M, Herth F, Duerschmied D, Schneider J, Schmid RM, Eberhardt JF, Khodamoradi Y, Vehreschild MJGT, Teufel A, Ebert MP, Hau P, Salzberger B, Schnitzler P, Poeck H, Elinav E, Merle U, Stein-Thoeringer CK. Correction to: Severe Dysbiosis and Specific Haemophilus and Neisseria Signatures as Hallmarks of the Oropharyngeal Microbiome in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients. Clin Infect Dis. 2022 May 10:ciac254. doi: 10.1093/cid/ciac254. Online ahead of print.PMID: 35536665 No abstract available.
Agamennone V, Abuja PM, Basic M, De Angelis M, Gessner A, Keijser B, Larsen M, Pinart M, Nimptsch K, Pujos-Guillot E, Schlicht K, Sharon I, Untersmayr E, Laudes M, Pischon T, Bouwman J, On Behalf Of The Consortium. HDHL-INTIMIC: A European Knowledge Platform on Food, Diet, Intestinal Microbiomics, and Human Health.
Nutrients. 2022 Apr 29;14(9):1881. doi: 10.3390/nu14091881.PMID: 35565847 Free PMC article.
Ghimire S, Ederer KU, Meedt E, Weber D, Matos C, Hiergeist A, Zeman F, Wolff D, Edinger M, Poeck H, Herr W, Gessner A, Holler E, Bülow S. Low Intestinal IL22 Associates With Increased Transplant-Related Mortality After Allogeneic Stem Cell Transplantation.
Front Immunol. 2022 Apr 29;13:857400. doi: 10.3389/fimmu.2022.857400. eCollection 2022.PMID: 35572572 Free PMC article.
Meister TL, Gottsauner JM, Schmidt B, Heinen N, Todt D, Audebert F, Buder F, Lang H, Gessner A, Steinmann E, Vielsmeier V, Pfaender S, Cieplik F. Mouthrinses against SARS-CoV-2 - High antiviral effectivity by membrane disruption in vitro translates to mild effects in a randomized placebo-controlled clinical trial. Virus Res. 2022 Jul 15;316:198791. doi: 10.1016/j.virusres.2022.198791. Epub 2022 May 2.PMID: 35504446 Free PMC article. Clinical Trial.
Glück V, Tydykov L, Mader AL, Warda AS, Bertok M, Weidlich T, Gottwald C, Köstler J, Salzberger B, Wagner R, Koller M, Gessner A, Schmidt B, Glück T, Peterhoff D.Humoral immunity in dually vaccinated SARS-CoV-2-naïve individuals and in booster-vaccinated COVID-19-convalescent subjects. Infection. 2022 Apr 11:1-7. doi: 10.1007/s15010-022-01817-8. Online ahead of print.PMID: 35403960 Free PMC article.
Glück V, Grobecker S, Köstler J, Tydykov L, Bertok M, Weidlich T, Gottwald C, Salzberger B, Wagner R, Zeman F, Koller M, Gessner A, Schmidt B, Glück T, Peterhoff D. Immunity after COVID-19 and vaccination: follow-up study over 1 year among medical personnel. Infection. 2022 Apr;50(2):439-446. doi: 10.1007/s15010-021-01703-9
Mader AL, Tydykov L, Glück V, Bertok M, Weidlich T, Gottwald C, Stefl A, Vogel M, Plentz A, Köstler J, Salzberger B, Wenzel JJ, Niller HH, Jantsch J, Wagner R, Schmidt B, Glück T, Gessner A, Peterhoff D. Omicron’s binding to Sotrovimab, Casirivimab, Imdevimab, CR3022, and sera from previously infected or vaccinated individuals. iScience. 2022 Mar 14:104076. doi: 10.1016/j.isci.2022.104076. Online ahead of print.PMID: 35309727 Free PMC article.
Peuker K; Strigli A, Tauriello D F V, Hendricks A, von Schönfels W, Burmeister G, Brosch M, Herrmann A, Krüger S, Nitsche J, Južnić L, Geissler M M, Hiergeist A, Gessner A, Wirbel M, Ponnudurai R P, Tunger A, Wehner R, Stange D E, Weitz J, Aust D E, Baretton G B, Schmitz M, Röcken C, Hampe J, Hinz S, Zeller G, Chavakis T, Schafmayer C, Batlle E, Zeissig S. Integration of microbial signals by myeloid calcineurin controls anti-tumor immunity in colorectal cancer. Immunity, 2022, in press.
Peterhoff D, Einhauser S, Beileke S, Niller HH, Günther F, Schachtner M, Asbach B, Steininger P, Tenbusch M, Peter AS, Gessner A, Burkhardt R, Heid IM, Wagner R, Überla K. Comparative Immunogenicity of COVID-19 Vaccines in a Population-Based Cohort Study with SARS-CoV-2-Infected and Uninfected Participants. Vaccines (Basel). 2022 Feb 18;10(2):324.
Schneider F, Gessner A, El-Najjar N. Efficacy of Vancomycin and Meropenem in Central Nervous System Infections in Children and Adults: Current Update. Antibiotics (Basel). 2022 Jan 28;11(2):173.
Ederer KU, Holzinger JM, Maier KT, Zeller L, Werner M, Toelge M, Gessner A, Bülow S. A Polymorphism of Bactericidal/Permeability-Increasing Protein Affects Its Neutralization Efficiency towards Lipopolysaccharide.Int J Mol Sci. 2022 Jan 25;23(3):132
Neumann B, Angstwurm K, Linker RA, Knoll G, Eidenschink L, Rubbenstroth D, Schlottau K, Beer M, Schreiner P, Soutschek E, Böhmer MM, Lampl BMJ, Pregler M, Scheiter A, Evert K, Zoubaa S, Riemenschneider MJ, Asbach B, Gessner A, Niller HH, Schmidt B, Bauswein M. Antibodies against viral nucleo-, phospho-, and X protein contribute to serological diagnosis of fatal Borna disease virus 1 infections. Cell Rep Med. 2022 Jan 18;3(1):100499
Pfab C, Abgaryan A, Danzer B, Mourtada F, Ali W, Gessner A, El-Najjar N . Ceftazidime and cefepime antagonize 5-fluorouracil's effect in colon cancer cells. BMC Cancer. 2022 Jan 31;22(1):125
Bauswein M, Peterhoff D, Plentz A, Hiergeist A, Wagner R, Gessner A, Salzberger B, Schmidt B, Bauernfeind S. Increased neutralization of SARS-CoV-2 Delta variant after heterologous ChAdOx1 nCoV-19/BNT162b2 versus homologous BNT162b2 vaccination. iScience. 2022 Feb 18;25(2):103694,
Hupf J, Burkhardt R, Gessner A, Maier-Stocker C, Zimmermann M, Hanses F, Peterhoff D. Low incidence of SARS-CoV-2 infections in healthcare workers at a tertiary care hospital : Results of a prospective serological cohort study of the first and second COVID 19 pandemic wave. Med Klin Intensivmed Notfallmed. 2022 Jan 3:1-5.
Lang S, Loibl M, Gläsner J, Simon M, Rupp M, Grad S, Neumann C, Alt V, Gessner A, Hanses F. Vertebral osteomyelitis is characterised by increased RANK/OPG and RANKL/OPG expression ratios in vertebral bodies and intervertebral discs. Eur Cell Mater. 2021 Nov 29;42:438-451.
Schuderer JG, Spörl S, Spanier G, Gottsauner M, Gessner A, Hitzenbichler F, Meier JK, Reichert TE, Ettl T. Surgical and remote site infections after reconstructive surgery of the head and neck: A risk factor analysis. Craniomaxillofac Surg. 2022 Feb;50(2):178-187.
Siska PJ, Decking SM, Babl N, Matos C, Bruss C, Singer K, Klitzke J, Schön M, Simeth J, Köstler J, Siegmund H, Ugele I, Paulus M, Dietl A, Kolodova K, Steines L, Freitag K, Peuker A, Schönhammer G, Raithel J, Graf B, Geismann F, Lubnow M, Mack M, Hau P, Bohr C, Burkhardt R, Gessner A, Salzberger B, Wagner R, Hanses F, Hitzenbichler F, Heudobler D, Lüke F, Pukrop T, Herr W, Wolff D, Spang R, Poeck H, Hoffmann P, Jantsch J, Brochhausen C, Lunz D, Rehli M, Kreutz M, Renner K. Metabolic imbalance of T cells in COVID-19 is hallmarked by basigin and mitigated by dexamethasone. J Clin Invest. 2021 Nov 15;131(22):e148225.
Ghimire S, Weber D, Hippe K, Meedt E, Hoepting M, Kattner AS, Hiergeist A, Gessner A, Matos C, Wolff D, Edinger M, Hoffmann P, Poeck H, Herr W, Holler E GPR Expression in Intestinal Biopsies From SCT Patients Is Upregulated in GvHD and Is Suppressed by Broad-Spectrum Antibiotics. GPR Expression in Intestinal Biopsies From SCT Patients Is Upregulated in GvHD and Is Suppressed by Broad-Spectrum Antibiotics. Front Immunol. 2021 Oct 28;12:753287
Hottenträger B, Hagedorn HJ, Bäcker E, Bleekmann B, Gessner A, Lübke N, Wenzel JJ, Widera M, Pabinger S, Ramge P, Timm J Multicenter Performance Evaluation of Elecsys Anti-HBc II, Anti-HCV II, HIV combi PT, HBsAg II, and Syphilis Immunoassays. Clin Lab. 2021 Nov 1;67(11).
Wahida A, Müller M, Hiergeist A, Popper B, Steiger K, Branca C, Tschurtschenthaler M, Engleitner T, Donakonda S, De Coninck J, Öllinger R, Pfautsch MK, Müller N, Silva M, Usluer S, Thiele Orberg E, Böttcher JP, Pfarr N, Anton M, Slotta-Huspenina JB, Nerlich AG, Madl T, Basic M, Bleich A, Berx G, Ruland J, Knolle PA, Rad R, Adolph TE, Vandenabeele P, Kanegane H, Gessner A, Jost PJ, Yabal M. XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells. Sci Immunol. 2021 Nov 5;6(65):eabf7235
Bauernfeind S, Salzberger B, Hitzenbichler F, Scigala K, Einhauser S, Wagner R, Gessner A, Koestler J, Peterhoff D. Association between Reactogenicity and Immunogenicity after Vaccination with BNT162b2 Vaccines (Basel). 2021 Sep 27;9(10):1089.
.de Castilhos J, Zamir E, Hippchen T, Rohrbach R, Schmidt S, Hengler S, Schumacher H, Neubauer M, Kunz S, Müller-Esch T, Hiergeist A, Gessner A, Khalid D, Gaiser R, Cullin N, Papagiannarou SM, Beuthien-Baumann B, Krämer A, Bartenschlager R, Jäger D, Müller M, Herth F, Duerschmied D, Schneider J, Schmid RM, Eberhardt JF, Khodamoradi Y, Vehreschild MJGT, Teufel A, Ebert MP, Hau P, Salzberger B, Schnitzler P, Poeck H, Elinav E, Merle U, Stein-Thoeringer CK Severe dysbiosis and specific Haemophilus and Neisseria signatures as hallmarks of the oropharyngeal microbiome in critically ill COVID-19 patients. Clin Infect Dis. 2021 Oct 25:ciab902.
Glück V, Grobecker S, Köstler J, Tydykov L, Bertok M, Weidlich T, Gottwald C, Salzberger B, Wagner R, Zeman F, Koller M, Gessner A, Schmidt B, Glück T, Peterhoff D Immunity after COVID-19 and vaccination: follow-up study over 1 year among medical personnel. Infection. 2021 Sep 25:1-8
Stanzick KJ, Li Y, Schlosser P, Gorski M, Wuttke M, Thomas LF, Rasheed H, Rowan BX, Graham SE, Vanderweff BR, Patil SB; VA Million Veteran Program, Robinson-Cohen C, Gaziano JM, O'Donnell CJ, Willer CJ, Hallan S, Åsvold BO, Gessner A, Hung AM, Pattaro C, Köttgen A, Stark KJ, Heid IM, Winkler TW. Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals Nat Commun. 2021 Jul 16;12(1):4350.
Pfab C, Schnobrich L, Eldnasoury S, Gessner A, El-Najjar N Repurposing of Antimicrobial Agents for Cancer Therapy: What Do We Know? Cancers (Basel). 2021 Jun 26;13(13):3193.
Wagner R, Peterhoff D, Beileke S, Günther F, Berr M, Einhauser S, Schütz A, Niller HH, Steininger P, Knöll A, Tenbusch M, Maier C, Korn K, Stark KJ, Gessner A, Burkhardt R, Kabesch M, Schedl H, Küchenhoff H, Pfahlberg AB, Heid IM, Gefeller O, Überla K. Estimates and Determinants of SARS-Cov-2 Seroprevalence and Infection Fatality Ratio Using Latent Class Analysis: The Population-Based Tirschenreuth Study in the Hardest-Hit German County in Spring 2020. Viruses. 2021 Jun 10;13(6):1118
Renner K, Schwittay T, Chaabane S, Gottschling J, Müller C, Tiefenböck C, Salewski JN, Winter F, Buchtler S, Balam S, Malfertheiner MV, Lubnow M, Lunz D, Graf B, Hitzenbichler F, Hanses F, Poeck H, Kreutz M, Orsó E, Burkhardt R, Niedermair T, Brochhausen C, Gessner A, Salzberger B, Mack M. Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomes. Nat Commun. 2021 May 21;12(1):3006
Meedt E, Hiergeist A, Gessner A, Dettmer K, Liebisch G, Ghimire S, Poeck H, Edinger M, Wolff D, Herr W, Holler E, Weber D Prolonged Suppression of Butyrate-Producing Bacteria Is Associated With Acute Gastrointestinal Graft-vs-Host Disease and Transplantation-Related Mortality After Allogeneic Stem Cell Transplantation Clin Infect Dis. 2022 Mar 1;74(4):614-621
Mao X, Jakubovics NS, Bächle M, Buchalla W, Hiller KA, Maisch T, Hellwig E, Kirschneck C, Gessner A, Al-Ahmad A, Cieplik F. Colonization of Helicobacter pylori in the oral cavity - an endless controversy? Crit Rev Microbiol. 2021 Sep;47(5):612-629.
Glück V, Grobecker S, Tydykov L, Salzberger B, Glück T, Weidlich T, Bertok M, Gottwald C, Wenzel JJ, Gessner A, Schmidt B, Peterhoff D. SARS-CoV-2-directed antibodies persist for more than six months in a cohort with mild to moderate COVID-19. Infection. 2021 Aug;49(4):739-746.
Basic M, Bolsega S, Smoczek A, Gläsner J, Hiergeist A, Eberl C, Stecher B, Gessner A, Bleich . Monitoring and contamination incidence of gnotobiotic experiments performed in microisolator cages. Int J Med Microbiol. 2021 Apr;311(3):151482
Evert K, Dienemann T, Brochhausen C, Lunz D, Lubnow M, Ritzka M, Keil F, Trummer M, Scheiter A, Salzberger B, Reischl U, Boor P, Gessner A, Jantsch J, Calvisi DF, Evert M, Schmidt B, Simon M. Autopsy findings after long-term treatment of COVID-19 patients with microbiological correlation. Virchows Arch. 2021 Jul;479(1):97-108.
Lubnow M, Schmidt B, Fleck M, Salzberger B, Müller T, Peschel G, Schneckenpointner R, Lange T, Hitzenbichler F, Kieninger M, Lunz D, Graf B, Brochhausen C, Weber F, Lüke F, Peterhoff D, Schuster P, Hiergeist A, Offner R, Hehr U, Wallner S, Hanses F, Schmid S, Weigand K, Geismann F, Poeck H, Pukrop T, Evert M, Gessner A, Burkhardt R, Herr W, Maier LS, Heudobler D. Secondary hemophagocytic lymphohistiocytosis and severe liver injury induced by hepatic SARS-CoV-2 infection unmasking Wilson's disease: Balancing immunosuppression. Int J Infect Dis. 2021 Feb;103:624-627
Hähnel V, Peterhoff D, Bäuerlein V, Brosig AM, Pamler I, Johnson C, Bica A, Totir M, Ossner T, Stemmer B, Toelge M, Schütz A, Niller HH, Schmidt B, Wagner R, Gessner A, Burkhard R, Offner R.I Manufacturing of convalescent plasma of COVID-19 patients: Aspects of quality. PLoS One. 2020 Dec 22;15(12):e0243967.
Cieplik F, Wiedenhofer AM, Pietsch V, Hiller KA, Hiergeist A, Wagner A, Baldaranov D, Linker RA, Jantsch J, Buchalla W, Schlachetzki F, Gessner A. Oral Health, Oral Microbiota, and Incidence of Stroke-Associated Pneumonia-A Prospective Observational Study. . Front Neurol 2020 Nov 6;11:528056.
Bülow S, Heyd R, Toelge M, Ederer KU, Schweda A, Blaas SH, Hamer OW, Hiergeist A, Wenzel JJ, Gessner A. Lipopolysaccharide Binding Protein and Bactericidal/Permeability-Increasing Protein as Biomarkers for Invasive Pulmonary Aspergillosis. J Fungi (Basel). 2020 Nov 20;6(4):304.
Lichtinger U, Greifenberg V, Gessner A. Antibiotic stewardship (ABS)-strategies for urologists in private practice and hospitals. Urologe A. 2020 Dec;59(12):1472-1479
Schwarz SR, Hirsch S, Hiergeist A, Kirschneck C, Muehler D, Hiller KA, Maisch T, Al-Ahmad A, Gessner A, Buchalla W, Cieplik FLimited antimicrobial efficacy of oral care antiseptics in microcosm biofilms and phenotypic adaptation of bacteria upon repeated exposure. Clin Oral Investig. 2021 May;25(5):2939-2950.
Peterhoff D, Glück V, Vogel M, Schuster P, Schütz A, Neubert P, Albert V, Frisch S, Kiessling M, Pervan P, Werner M, Ritter N, Babl L, Deichner M, Hanses F, Lubnow M, Müller T, Lunz D, Hitzenbichler F, Audebert F, Hähnel V, Offner R, Müller M, Schmid S, Burkhardt R, Glück T, Koller M, Niller HH, Graf B, Salzberger B, Wenzel JJ, Jantsch J, Gessner A, Schmidt B, Wagner R. A highly specific and sensitive serological assay detects SARS-CoV-2 antibody levels in COVID-19 patients that correlate with neutralization. Infection. 2021 Feb;49(1):75-82.
Hiergeist A, Gessner J, Gessner A. Current Limitations for the Assessment of the Role of the Gut Microbiome for Attention Deficit Hyperactivity Disorder (ADHD). Front Psychiatry. 2020 Jun 26;11:623.
Danzer H, Glaesner J, Baerenwaldt A, Reitinger C, Lux A, Heger L, Dudziak D, Harrer T, Gessner A, Nimmerjahn F. Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis. Elife. 2020 Jul 2;9:e55319
Stolte M, Ali W, Jänis J, Gessner A, El-Najjar N. Paclitaxel, Imatinib and 5-Fluorouracil Increase the Unbound Fraction of Flucloxacillin In Vitro. Antibiotics (Basel). 2020 Jun 8;9(6):309
Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD. The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation. Nat Commun. 2020 May 8;11(1):2306.
Pamler I, Richter E, Hutchinson JA, Hähnel V, Holler E, Gessner A, Burkhardt R, Ahrens N. Bacterial contamination rates in extracorporeal photopheresis. Transfusion. 2020 Jun;60(6):1260-1266.
Peled JU, Gomes ALC, Devlin SM, Littmann ER, Taur Y, Sung AD, Weber D, Hashimoto D, Slingerland AE, Slingerland JB, Maloy M, Clurman AG, Stein-Thoeringer CK, Markey KA, Docampo MD, Burgos da Silva M, Khan N, Gessner A, Messina JA, Romero K, Lew MV, Bush A, Bohannon L, Brereton DG, Fontana E, Amoretti LA, Wright RJ, Armijo GK, Shono Y, Sanchez-Escamilla M, Castillo Flores N, Alarcon Tomas A, Lin RJ, Yáñez San Segundo L, Shah GL, Cho C, Scordo M, Politikos I, Hayasaka K, Hasegawa Y, Gyurkocza B, Ponce DM, Barker JN, Perales MA, Giralt SA, Jenq RR, Teshima T, Chao NJ, Holler E, Xavier JB, Pamer EG, van den Brink MRM. Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation. N Engl J Med. 2020 Feb 27;382(9):822-834.
Niller HH, Angstwurm K, Rubbenstroth D, Schlottau K, Ebinger A, Giese S, Wunderlich S, Banas B, Forth LF, Hoffmann D, Höper D, Schwemmle M, Tappe D, Schmidt-Chanasit J, Nobach D, Herden C, Brochhausen C, Velez-Char N, Mamilos A, Utpatel K, Evert M, Zoubaa S, Riemenschneider MJ, Ruf V, Herms J, Rieder G, Errath M, Matiasek K, Schlegel J, Liesche-Starnecker F, Neumann B, Fuchs K, Linker RA, Salzberger B, Freilinger T, Gartner L, Wenzel JJ, Reischl U, Jilg W, Gessner A, Jantsch J, Beer M, Schmidt B. Zoonotic spillover infections with Borna disease virus 1 leading to fatal human encephalitis, 1999-2019: an epidemiological investigation. Lancet Infect Dis. 2020 Apr;20(4):467-477.
Plössl K, Straub K, Schmid V, Strunz F, Wild J, Merkl R, Weber BHF, Friedrich U1 (2019) Identification of the retinoschisin-binding site on the retinal Na/K-ATPase. PLoS One 14(5):e0216320. PMID: 31048931
Bülow S, Zeller L, Werner M, Toelge M, Holzinger J, Entzian C, Schubert T, Waldow F, Gisch N, Hammerschmidt S, Gessner A (2018) Bactericidal/Permeability-Increasing Protein Is an Enhancer of Bacterial Lipoprotein Recognition. Front Immunol 9:2768, PMID: 30581431
Brandstetter S, Toncheva AA, Niggel J, Wolff C, Gran S, Seelbach-Göbel B, Apfelbacher C, Melter M, Kabesch M; KUNO-Kids study group; Collaborators: Arndt P, Baessler A, Berneburg M, Buchalla W, Fill Malfertheiner S, Gessner A, Heid I, Kerzel S, Koller M, Leitzmann M, Rothfuß D, Rösch W, Segerer H, Weber BHF, Weidinger S (2018) KUNO-Kids birth cohort study: rationale, design, and cohort description. Mol Cell Pediatr 6(1):1, PMID: 30627823
Simon M, Gatermann S, Pfeifer Y, Reischl U, Gessner A, Jantsch J (2018) Evaluation of the automated BD Phoenix CPO Detect panel in combination with the β-CARBA assay for detection and classification of carbapenemase-producing Enterobacterales. J Microbiol Methods 156:29-33, PMID: 30521867
Weber D, Hiergeist A, Weber M, Dettmer K, Wolff D, Hahn J, Herr W, Gessner A, Holler E (2018) Detrimental effect of broad-spectrum antibiotics on intestinal microbiome diversity in patients after allogeneic stem cell transplantation: Lack of commensal sparing antibiotics. Clin Infect Dis [Epub ahead of print], PMID: 30124813
Zach F, Polzer F, Mueller A, Gessner A (2018) p62/sequestosome 1 deficiency accelerates osteoclastogenesis in vitro and leads to Paget's disease-like bone phenotypes in mice. J Biol Chem 293(24):9530-9541, PMID: 29555685
Hösl J, Gessner A, El-Najjar N (2018) Liquid chromatography-tandem mass spectrometry for the quantification of moxifloxacin, ciprofloxacin, daptomycin, caspofungin, and isavuconazole in human plasma. J Pharm Biomed Anal 157:92-99, PMID: 29777985
Simon M, Richert K, Pfennigwerth N, Pfeifer Y, Reischl U, Gatermann S, Gessner A, Jantsch J (2018) Carbapenemase detection using the β-CARBA test: Influence of test conditions on performance and comparison with the RAPIDEC CarbaNP assay. J Microbiol Methods 147:17-19, PMID: 29427685
Hiergeist A, Gessner A (2018) The human intestinal microbiome and why you have to think twice before prescribing antibiotics! MMW Fortschr Med 160(1):58-62, PMID: 29335940
Brenner D, Hiergeist A, Adis C, Mayer B, Gessner A, Ludolph AC, Weishaupt JH (2018) The fecal microbiome of ALS patients. Neurobiol Aging 61:132-137 PMID: 29065369
Dilger T, Melzl H, Gessner A (2017) Legionella contamination in warm water systems: A species-level survey. Int J Hyg Environ Health S1438-4639(17)30535-7, PMID: 29108681
Dietze-Schwonberg K, Lorenz B, Lopez Kostka S, Schumak B, Gessner A, von Stebut E (2017) Insufficient generation of Th17 cells in IL-23p19-deficient BALB/c mice protects against progressive cutaneous leishmaniasis. Exp Dermatol, PMID: 29078003
Weber D, Frauenschläger K, Ghimire S, Peter K, Panzer I, Hiergeist A, Weber M, Kutny D, Wolff D, Grube M, Huber E, Oefner P, Gessner A, Hehlgans T, Herr W, Holler E (2017) The association between acute graft-versus-host disease and antimicrobial peptide expression in the gastrointestinal tract after allogeneic stem cell transplantation. PLoS One 12(9):e0185265, PMID: 28934349
Asare Y, Ommer M, Azombo FA, Alampour-Rajabi S, Sternkopf M, Sanati M, Gijbels MJ, Schmitz C, Sinitski D, Tilstam PV, Lue H, Gessner A, Lange D, Schmid JA, Weber C, Dichgans M, Jankowski J, Pardi R, de Winther MP, Noels H, Bernhagen J (2017) Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo. Proc Natl Acad Sci U S A 114(13):E2766-E2775
El-Najjar N, Hösl J, Holzmann T, Jantsch J, Gessner A (2017) UPLC-MS/MS method for therapeutic drug monitoring of 10 antibiotics used in intensive care units. Drug Test Anal, PMID: 28753737
Lukas K, Stadtherr K, Gessner A, Wehner D, Schmid T, Wendel HP, Schmid C, Lehle K (2017) Effect of Immobilized Antithrombin III on the Thromboresistance of Polycarbonate Urethane. Materials (Basel) 10(4), PMID: 28772696
Naber KG, Kogan M, Wagenlehner FME, Siener R, Gessner A (2017) How the microbiome is influenced by the therapy of urological diseases: standard versus alternative approaches. Clinical Phytoscience 3:8
El-Najjar N, Jantsch J, Gessner A (2017) A rapid liquid chromatography-tandem mass spectrometry for the quantification of Fosfomycin in plasma, urine, and aqueous fluids. J Chromatogr B Analyt Technol Biomed Life Sci 1061-1062:57-64
Greimel F, Scheuerer C, Gessner A, Simon M, Kalteis T, Grifka J, Benditz A, Springorum HR, Schaumburger J (2017) Efficacy of antibiotic treatment of implant-associated Staphylococcus aureus infections with moxifloxacin, flucloxacillin, rifampin, and combination therapy: an animal study. Drug Des Devel Ther 11:1729-1736. doi: 10.2147/DDDT.S138888
Plössl K, Royer M, Bernklau S, Tavraz NN, Friedrich T, Wild J, Weber BHF, Friedrich U (2017) Retinoschisin is linked to retinal Na/K-ATPase signaling and localization. Mol Biol Cell [Epub ahead of print] PMID: 28615319
Simon M, Held I, Teichmann L, Köstler J, Gessner A, Schmidt B, Jantsch J (2017) Liquillizer Does Not Interfere with Galactomannan Antigen Detection in Contrast to Dithiothreitol and N-Acetyl-l-Cysteine. J Clin Microbiol 55(6):1964-1965; PMID: 28381606
Weber D, Jenq RR, Peled JU, Taur Y, Hiergeist A, Koestler J, Dettmer K, Weber M, Wolff D, Hahn J, Pamer EG, Herr W, Gessner A, Oefner PJ, van den Brink MR, Holler E (2017) Microbiota Disruption Induced by Early Use of Broad-Spectrum Antibiotics Is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant 23(5):845-852; PMID: 28232086
Simon M, Melzl H, Hiergeist A, Richert K, Falgenhauer L, Pfeifer Y, Gerlach RG, Fuchs K, Reischl U, Gessner A, Jantsch J (2017) Colistin- and carbapenem-resistant Klebsiella oxytoca harboring blaVIM-2 and an insertion in the mgrB gene isolated from blood culture. Int J Med Microbiol 307(2):113-115; PMID: 28122677
El-Najjar N, Jantsch J, Gessner A (2017) The use of liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring of antibiotics in cancer patients. Clin Chem Lab Med; PMID: 28076304
Bouazzaoui A, Huber E, Dan A, Al-Allaf FA, Pfirstinger J, Sprotte G, Köstler J, Hiergeist A, Gessner A, Herr W, Holler E (2016) Reduction of aGvHD using chicken antibodies directed against intestinal pathogens in a murine model. Blood; PMID: 28011676
Schatz V, Strüssmann Y, Mahnke A, Schley G, Waldner M, Ritter U, Wild J, Willam C, Dehne N, Brüne B, McNiff JM, Colegio OR, Bogdan C, Jantsch J (2016) Myeloid Cell-Derived HIF-1α Promotes Control of Leishmania major. J Immunol 197(10):4034-4041; PMID: 27798163
Hiergeist A, Gessner A (2016) Clinical implications of the microbiome in urinary tract diseases. Curr Opin Urol; PMID: 27898455
Altenbuchinger M, Rehberg T, Zacharias HU, Stämmler F, Dettmer K, Weber D, Hiergeist A, Gessner A, Holler E, Oefner PJ, Spang R (2016) Reference point insensitive molecular data analysis. Bioinformatics; PMID: 27634945
Weber D, Oefner PJ, Dettmer K, Hiergeist A, Koestler J, Gessner A, Weber M, Stämmler F, Hahn J, Wolff D, Herr W, Holler E (2016) Rifaximin preserves intestinal microbiota balance in patients undergoing allogeneic stem cell transplantation. Bone Marrow Transplant 51(8):1087-92; PMID: 26999466
Stämmler F, Gläsner J, Hiergeist A, Holler E, Weber D, Oefner PJ, Gessner A, Spang R (2016) Adjusting microbiome profiles for differences in microbial load by spike-in bacteria. Microbiome 4:28; DOI 10.1186/s40168-016-0175-0
Dilger T, Melzl H, Gessner A (2016) Rapid and reliable identification of waterborne Legionella species by MALDI-TOF mass spectrometry. J Microbiol Methods 127 pp 154-159; PMID: 27260989
Pinkenburg O, Meyer T, Bannert N, Norley S, Bolte K, Czudai-Matwich V, Herold S, Gessner A, Schnare M (2016) The Human Antimicrobial Protein Bactericidal/Permeability-Increasing Protein (BPI) Inhibits the Infectivity of Influenza A Virus. PLoS One 6;11(6):e0156929; PMID: 27273104
Hiergeist A, Reischl U, Priority Program 1656 Intestinal Microbiota Consortium/quality assessment participants, Gessner A(2016) Multicenter quality assessment of 16S ribosomal DNA-sequencing formicrobiome analyses reveals high inter-center variability. Int J Med Microbiol; PMID: 27052158
Krzyzak L, Seitz C, Urbat A, Hutzler S, Ostalecki C, Gläsner J, Hiergeist A, Gessner A, Winkler TH, Steinkasserer A, Nitschke L (2016) CD83 Modulates B Cell Activation and Germinal Center Responses. J Immunol; PMID: 26983787
Weber D, Oefner PJ, Dettmer K, Hiergeist A, Koestler J, Gessner A, Weber M, Stämmler F, Hahn J, Wolff D, Herr W, Holler E (2016) Rifaximin preserves intestinal microbiota balance in patients undergoing allogeneic stem cell transplantation. Bone Marrow Transplant; PMID: 26999466
Kesselring R, Glaesner J, Hiergeist A, Naschberger E, Neumann H, Brunner SM, Wege AK, Seebauer C, Köhl G, Merkl S, Croner RS, Hackl C, Stürzl M, Neurath MF, Gessner A, Schlitt HJ, Geissler EK, Fichtner-Feigl S (2016) IRAK-M Expression in Tumor Cells Supports Colorectal Cancer Progression through Reduction of Antimicrobial Defense and Stabilization of STAT3. Cancer Cell, available online 14 April 2016; doi:10.1016/j.ccell.2016.03.014
Dilger T, Melzl H, Gessner A (2016) Legionellen-Kontaminationen in Warmwassersystemen in Deutschland - Einfluss der maximal erreichbaren Temperatur und der Temperatur bei der Probenahme. gwf-Wasser/Abwasser, Ausgabe 03 2016
Lukas K, Thomas U, Gessner A, Wehner D, Schmid T, Schmid C, Lehle K (2016) Plasma functionalization of polycarbonaturethane to improve endothelialization—Effect of shear stress as a critical factor for biocompatibility control. Journal of Biomaterials Applications, Published online before print January 12, 2016, PMID: 26762398
Zach F, Mueller A, Gessner A (2015) Production and Functional Characterization of Murine Osteoclasts Differentiated from ER-Hoxb8-Immortalized Myeloid Progenitor Cells. PLoS ONE 10:e0142211; PMID: 26529319
Hiergeist A, Gläsner J, Reischl U, Gessner A (2015) Analyses of Intestinal Microbiota: Culture versus Sequencing. ILAR J 56(2):228-40; PMID: 26323632
Weber D, Oefner PJ, Hiergeist A, Koestler J, Gessner A, Weber M, Hahn J, Wolff D, Stämmler F, Spang R, Herr W, Dettmer K, Holler E (2015) Low urinary indoxyl sulfate levels early after ASCT reflect a disrupted microbiome and are associated with poor outcome. Blood 24 [Epub ahead of print]; PMID: 26209659
Knop J, Hanses F, Leist T, Archin NM, Buchholz S, Gläsner J, Gessner A, Wege AK (2015) Staphylococcus aureus Infection in Humanized Mice: A New Model to Study Pathogenicity Associated With Human Immune Response. J Infect Dis pii: jiv073 [Epub ahead of print]; PMID: 25657257
Holler E, Butzhammer P, Schmid K, Hundsrucker C, Koestler J, Peter K, Zhu W, Sporrer D, Hehlgans T, Kreutz M, Holler B, Wolff D, Edinger M, Andreesen R, Levine JE, Ferrara JL, Gessner A, Spang R, Oefner PJ (2014) Metagenomic Analysis of the Stool Microbiome in Patients Receiving Allogeneic Stem Cell Transplantation: Loss of Diversity Is Associated with Use of Systemic Antibiotics and More Pronounced in Gastrointestinal Graft-versus-Host Disease. Biol Blood Marrow Transplant 20(5):640-5; PMID: 24492144
Goldwich A, Burkard M, Ölke M, Daniel C, Amann K, Hugo C, Kurts C, Steinkasserer A, Gessner A (2013) Podocytes are nonhematopoietic professional antigen-presenting cells. J Am Soc Nephrol 24(6):906-16; PMID: 23539760
Goldwich A, Steinkasserer A, Gessner A, Amann K (2012) Impairment of podocyte function by diphtheria toxin-a new reversible proteinuria model in mice. Lab Invest 92:1674-85; PMID: 23007132
Rückert C, Licht K, Kalinowski J, Espírito Santo C, Antwerpen M, Hanczaruk M, Reischl U, Holzmann T, Gessner A, Tiemann C, Grass G (2012) Draft Genome Sequence of Bacillus anthracis UR-1, Isolated from a German Heroin User. J Bacteriol 194:5997-8; PMID: 23045504
Holzmann T, Frangoulidis D, Simon M, Noll P, Schmoldt S, Hanczaruk M, Grass G, Pregler M, Sing A, Hörmansdorfer S, Bernard H, Grunow R, Zimmermann R, Schneider-Brachert W, Gessner A, Reischl U (2012) Fatal anthrax infection in a heroin user from southern Germany, June 2012. Euro Surveill 17; PMID: 22790532
Sitte S, Gläsner J, Jellusova J, Weisel F, Panattoni M, Pardi R, Gessner A (2012) JAB1 is essential for B cell development and germinal center formation and inversely regulates Fas ligand and Bcl6 expression. J Immunol 188:2677-86; PMID: 22327073
Böckl K, Wild J, Bredl S, Kindsmüller K, Köstler J, Wagner R (2012) Altering an artificial GagPolNef polyprotein and mode of Env co-administration affects the immunogenicity of a clade C HIV DNA vaccine. PLoS ONE 7:e34723; PMID: 22509350
Klaffenbach D, Friedrich D, Strick R, Strissel PL, Beckmann MW, Rascher W, Gessner A, Dötsch J, Meissner U, Schnare M (2011) Contribution of different placental cells to the expression and stimulation of antimicrobial proteins (AMPs). Placenta 32:830-7
Agwale SM, Forbi JC, Notka F, Wrin T, Wild J, Wagner R, Wolf H (2011) Broad Antibody Mediated Cross-Neutralization and Preclinical Immunogenicity of New Codon-Optimized HIV-1 Clade CRF02_AG and G Primary Isolates. PLoS One 6:e23233
Schulze J, Bickert T, Beil FT, Zaiss MM, Albers J, Wintges K, Streichert T, Klaetschke K, Keller J, Hissnauer TN, Spiro AS, Gessner A, Schett G, Amling M, McKenzie AN, Horst AK, Schinke T (2011) Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells. J Bone Miner Res 26:704-17
Jantsch J, Wiese M, Schödel J, Castiglione K, Gläsner J, Kolbe S, Mole D, Schleicher U, Eckardt KU, Hensel M, Lang R, Bogdan C, Schnare M, Willam C (2011) Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression. J Leukoc Biol 90:551-62
First description of cytokine Elispot technique
Gessner A, Moskophidis D, Lehmann-Grube F (1989) Enumeration of single interferon-gamma producing cells in mice during viral and bacterial infection. J Immunol 142:1293-9